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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ce916f94b2d126dcfae2589ebcd78dd250a1c615d79f695a67d4182971f000' 
  AND token = 'MXbLvYTv5TqS564qe01mG+d8y4wp/46+51UrUkH5Cu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}