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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7597487f2817ecc5ad7a6aa98db05ba117e18c2d89fba61383e3b09ea87a234' 
  AND token = 'c0GQkd2nDFJ/xKgx9epbNPLs1nb29nxg+DSXDcCAS0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}