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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c729ebd8dedd565886f533cc0bc4d0226655a089263041c4d1bebc80d7ede5' 
  AND token = 'cAm4whtCTwhAsJvmf5X+jKjCnGGcIpuB9RQr2viN/nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}