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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7f9e1b941dce62e2ac2ae3784dd7be1863d56b0b65384b58817862338aa438' 
  AND token = 'C327IujlOkKzKeBMKCEGECPmZi6y/o2lYmSQPsgi0EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}