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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16441f3069023082c94d1227e2c79edf1a443d628926f75e1c5529fd305a0f46' 
  AND token = 'ZFBnnGnNPwqiU5ywn71msnB9oHSwR9XbGQM+RmKcW/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}