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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8915f078f5c9e78b0286972139dbccde2c5a63ad5e4d8c6ea4e5deb1c1ad2fad' 
  AND token = '4nrOGkrdL5gpoJ8lw8a6ylOCRbmvm+ZutTZjtLhLxao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}