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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41bc0acb4e6cedfd798367e235874d4abeeeeb45f93980cbe521e9cad82a647' 
  AND token = 'Ep1gRcmQXNNarj4FzHW+oo+BYN9wQtUX7gsaz5IJA28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}