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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dd447ffd4b2c4fd4530b88827c18c883679b380da68dd8f24686d5ed9d35e85' 
  AND token = 'QPiDWu+qEtxMMg+fS9VMF3zz7z0sBEGqcKDXrfPlEsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}