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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53cf905b1a32cf19b1f3edb93c3827947dbbda2b991bed3687d7b17d6d86356c' 
  AND token = 'eWAsaRJ37kbJGXaAIZmo2KypYVEb2Jhc5Yw2JNBTVSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}