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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1d49b510e231ee5536d88ff7c1d21701ca09bb551d1dab397528e8580261d27' 
  AND token = 'ZwrPWn73DoZIkx9qNACQeMmvIEVDBU88tne0uxE6SWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}