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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1750d9b75ea5dc1e6558884866a0445cddfe2c5ad8e0a2ddccff52d520e797e5' 
  AND token = 'z9uJ2+ITCFW2hy4wD1+c4SiEjD8dyxFPYSoTB6Z0xws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}