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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd61b3ec035163d0e2d74f4e6b5bb3893ec10ed2300acb13ed35c47f889a076b0' 
  AND token = 'QK72VrdeEFCl2+hj3MiZW7dOHZ8xFx8zzfQ/UYcYR9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}