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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a58fabc6327e8f3041eb314099f20cb008135619325b9b0e2b2c05c27ea2b2cf' 
  AND token = 'E+Oi9ilBWwauFP1lS730BH087iu8DleUz6vZCXOT6vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}