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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48979a0998d7272cd7f53b2325101b53adb9e5ae196a69043de1f54cbe5be2d8' 
  AND token = 'Zq1LZEu8KA/ktmI+CfZEuyfZvPkf/RPsFl6XR3DuGrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}