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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3374b551ff89724c0eaaddca399087ff9e4d9ed4ff1cf38468f82d4ee7afecc' 
  AND token = 'CyA75mldhL2pQHz6EejmVlKu2h9d4rPUsT2ToG82yaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}