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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b7035352f0d99f18609df89e059a0c2079585750862f31f80cdc170df38ddc' 
  AND token = 'qkWqlrJy0F6sM/ssvmzU63F5oDPpYkHip5xncN0wqR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}