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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8be26edf81a4daae66a3b4644bccc2a48826d9b5d962a85e9d67b6a015f24f09' 
  AND token = 'iJayQtl1Q6P6PZKi4KuSSYMdTo+za9dVVZ+GP9Gd0WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}