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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f33c8def41bbf881c9a8b8249427713328a166224298a6513a280ebeab2ff12' 
  AND token = '6yJxX/wrc1v1WndF0TZgBM/rwmYQPEE6w95iJHEGajY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}