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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00818fd887a0adab71482d3883b54c912b2a9d3a854debc7a514eab4e2d57698' 
  AND token = 'bIrkhlzSjBYt+4tz3oLW/9XW4UXSV31hOZmi8C+LFBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}