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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f6aa4225d407d5f3b4d036624f415a6d1cece3dda38f1f9c200eb4b0266aeb' 
  AND token = 'ACkj/tPWc9VzulltYR41o5SgfptdrldnBzbKLeyLqDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}