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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81ac02009399105cdf1de69a51738259ab5bb341bdf51c56e4d52f9a8bea6d5' 
  AND token = 'z5m9qDhG8+8jSXdDiJSgZiuNgmHr5WFK391Z+vfI4II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}