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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cbaf2b2a841619458a5d4cbd442cc0aaea4f7876bd3a2964b1549756571799' 
  AND token = 'xiyIZF9xWYgLPcJFxjo1zXoPTi1arCEBQtxLk4p6kU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}