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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7492e35b7732079db2c79ac04c5fc1916cd1243b47d6032bc8123b6ea05d2f' 
  AND token = 'vdS7/GWsuiuKVK3SLm7NkKzFQI5dyv7FLev+fbn2mQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}