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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7342d5cf4a869ba80ce5e6c6deb121cfca4106349bd894d18b67b779d93a3f' 
  AND token = '/uQ7RI8HcoDEXMG4NPViiqPM5T5/uAClZ5RfkZtoIx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}