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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881fc15f4a68292e9522015d582bd93846d6d9d1468575c62bad711bb246b6e2' 
  AND token = 'K2XGtyOk/e0iu9C7IU/m+EP3jmQ7KKpbOySC0xLAg8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}