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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c330b260b45a7db47a6d3fe8a66b8a561700997fc559c9894d9d17fa43560e9d' 
  AND token = '1DlOrO36/2DoJUPyA4Mvr1/uIMwbxC74lN50+1qxWRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}