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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2ca10101aeec638edaa08e13f0748c65797ff48af2bfcb952ae851f0d94141f' 
  AND token = 'eNXh1cKHG9nNSILgUV7IMgfYdFUk8ZDbMKM0HQtN4eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}