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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f3f370b2c590a80211a7604314d806f81ed9382de39d7ab03a6b2dc818ddc3' 
  AND token = 'yatjklRgk/E8QEQtwSzoeVyb9642kS38GMIoh4F2mv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}