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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '190d506217dcee0dd9cf397b4425a0e2d774c4f9634e17035708675e7f75f27d' 
  AND token = 'tzH1CwHSlQ5Xcekr1jaQLVXHR0pEiyWRy6DKH2PNbzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}