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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ae7c5ace5deebfc17af8f147e43e925722a01363b9b963531f60a279839feb5' 
  AND token = 'xKPwfnwpC7cMavEvkZ+3nWcPX5zzEh3H1KWASQwFbrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}