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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef1e3c974d812818af68e1d90a680252f2f36fe02998a2f251fdec5f1398a87' 
  AND token = '4jrpTS4O36TUTGFxDwDZhQa8mMBpEl+WXfMUpAGEaIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}