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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e420dda3ae749d5d4945d1a121f37b1244f7679058d80c45bcbfb872900a154c' 
  AND token = 'ipoj0EDc18KqOg/zMSQVs8pYzw7hSWdX5+vOTAdAn3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}