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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b26d14e015a28b8707d73c618d261442ef0936e8fdb21839e0775698d4a56c7' 
  AND token = '1LwZ+GGHqAvGDt7A20DLefXl/utdgBfhxMR0p4cQ1eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}