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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5018074eb67601543f3cda91b6dce45e37e1db5a7a31692434012701c65bcf' 
  AND token = 'VmT0mIYGlJhAWpd0TRDVRwa2vCdPxY9qw3r6Tn5wD40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}