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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ac3849cdb326edc85587837675a8f037099f4c1f1e8c12aa38b715209711fe' 
  AND token = '/0DeO0eYbmgc0oCrB3J4R0GPAuuiCMhRuEVz0XW+8Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}