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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35801c78d897f1f348c5f4dc46ba745e88f0e0c93364e2ac8a1f812adce9e117' 
  AND token = 'o1xAHERvG6Ygj1EnAgU9dY7JAoJ7krJEu3jf9Pvc+oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}