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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ac8760ac05a4457006a236739a57ab83062e9d5bc0a6984fc9079d1aafd85e' 
  AND token = 'm8gRdsRcN4wmxPDL5uhlhMGTL+w93ohe2fUPWj9hktk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}