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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1dcace9b2d05af72e3b9848e88ff9886071823df6be8027707f4fe47bb4431' 
  AND token = '8R2bB72acfiksiOcXFfCBoSU5FGOy+LUM0sEBdtDWfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}