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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6633dbb151e3e86b67bff09330f0b36495c8b9b1e4c30f26020de6f00397d6f0' 
  AND token = 'nxnV6kJm8C1/FA4z+KJvj39XAxyOpHWCIMBufFsoAQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}