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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5366dcc7bd31972681fb5ab637a450fd1a7ee044352df76f14d32fbe217a4d3' 
  AND token = 'wQ4GDSM/uImE0AzY/32+N8SLhDnIb7HUsFAR2ph81N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}