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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6465709bc9f40b14dc58bad005b93bcb668dddd6b8067ae4a7fc140effd38305' 
  AND token = '0IjBzxzy55iDx9PRgF4zzbFek1Dn1huRukZEX+9/t60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}