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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77d276d48f2d2a61ed4306fda6e1abe11945b2d0d3cfbeb2777d777793cd24ef' 
  AND token = 'XiFJdSc4r8gvcf7K7OmIaz2urmm8hZ/ZrHmS6LGvyB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}