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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ffda90d4f759dde6a83d455fb10ae7f3f721091b572c5d31714808a4f1eba22' 
  AND token = 'HA3Yo1+XOYKtqT23bv0JQcmje2yBUVoik76313vWSYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}