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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256868407c097f13d323f8c9cc200a1364a9e87a9e023868833b04449d8b3bce' 
  AND token = 'Joy8VcvDV77Z/U209lXH/Z1TnHOQeD+q6/wa2uu/xJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}