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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '414f81451c8e572fa036f51d11c4eb9f64b10c5ace65d5ce0228952ce1672bef' 
  AND token = 'yNE9GwmA6PKKYk8CM6cnIUd8PIgMkT3GGk1EC8n2m88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}