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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca8d4174438003d8891314e72fda6e6a3bd28f6f69e639b469e69bba3eda4141' 
  AND token = 'tm7jUUvR3UTV3o42BnDg2NUlWqvCQA5U9HvyO6wTnQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}