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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa0bf34892fe53068cec0779871a72f0dce521409100fa4223b2d8f455a4b3f' 
  AND token = 'vF40UqQbTRJWl8QNcWtFHF14zVN96thCCg5d2ayONUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}