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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e04e5dacdd2956b119b11719fa86baa36381488fb69b77ec4aa1d3aa598f15f6' 
  AND token = 'JSXW2/U7Ifr1NbQ3sZnHSHxgAICOaCd3UoQ4DwXFEKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}