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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '719851cb110239d6afccaf4221274e5a0b0fad06c14a69bc31ddf21d7ab75290' 
  AND token = 'ReA6Ppu37YS0h/Ti2WKlXNdhECikwxtCSgqxStAGG4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}