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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38278228bc627836724fdc8c228371aa8dd868c1f01410b8e6bcc5670ded694' 
  AND token = 'HORctOW7asJwuKgIPMLQZkyT1vkCxn86bKJ/5INfPZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}